Create a 30% bio-engineered liver mass for transplantation in patients with acute or acute-on-chronic liver failure.
PROJECT BACKGROUND
The possibility of producing bioengineered extrahepatic bile ducts of various lengths (up to 7-8 cm) will have a major impact on the current transplant and HPB surgical techniques. This is particularly important in the case of a “split-liver” transplant, i.e. when a large donor liver is split in two to be transplanted in two recipients and in the surgery of congenital biliary disease such as biliary atresia and Alagille syndrome.